Tacklin' Fantasy: Week 6 outlook
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Editor's note: Welcome to the weekly installment of "Tacklin' Fantasy," our recap of the news and trends you need to keep top of mind for fantasy dominance

49er to start: Vernon Davis, TE

To be frank, the Arizona Cardinals can’t stop opposing tight ends. In two of their five games this year, the position has gained over 130 yards receiving. Paired with Vernon Davis' ability for the big play -- he's averaging 16 yards per reception and had a 64 yard touchdown catch last week -- and he could be in line for a big game.

Raider to start: Denarius Moore, WR

In the first five weeks of the 2013 season, Denarius Moore has cemented himself as the Raiders No. 1 receiving option, leading the team in targets, receptions, yards, and receiving touchdowns. He has the speed to cause problems for the Raiders' Week 6 opponent, the Kansas City Chiefs. In each of the past four weeks, the Chiefs have given up a 40-plus yard pass to opponents, three to No. 1 wide receivers.

49er to sit: Frank Gore, RB

In the past three games, 49ers running back Frank Gore has been a stud with 48 carries for 316 yards and two touchdowns. The bad news? In Week 6, the 49ers play the Arizona Cardinals and their third-ranked rushing defense, against which no back has gained more than 65 yards. In his past two games against the Cardinals, Gore hasn’t fared well running the ball, either, amassing only 123 yards on 36 carries (3.42 average). Don’t expect another big game from the nine-year veteran this Sunday.

Raider to sit: Darren McFadden, Rashad Jennings, Marcel Reece, RB

No matter the status of Raiders running backs Darren McFadden and Rashad Jennings for Week 6, whoever starts will have a rough matchup against the Chiefs. Kansas City has held opposing running backs under 60 yards in four of its five games this year, including last week when they limited Tennessee Titans running back Chris Johnson to 17 yards on 10 carries.

[RELATED: McFadden, Jennings back at Raiders practice]

NFL Week 6 trend: New quarterback in Philadelphia

With Philadelphia Eagles starting quarterback Michael Vick injured, it will be second-year pro Nick Foles starting in Week 6. Foles doesn’t possess Vick's running ability or his arm strength, but he should improve on the starter's 53.8 percent completion percentage and provide a higher frequency of short, catchable passes for receivers Desean Jackson and Jason Avant. One potential fantasy downside is that defenses will be able to key in on running back LeSean McCoy in the absence of a dual-threat quarterback. With Vick at the helm last week, McCoy rushed 12 times for 48 yards and a score; with Foles under center, McCoy rushed eight times for minus-two yards.

NFL Week 6 trend: Atlanta Fail-cons

The Atlanta Falcons have been ravaged by injuries at key positions this year. Running back Steven Jackson (hamstring), wide receiver Roddy White (first ankle, then hamstring), and Julio Jones (foot) are all banged up. The Falcons mercifully have a bye to get healthy this week, but reports indicate it could take much longer for Jones, who leads the NFL with 41 catches and is second with 580 receiving yards. If Roddy White cannot play in Week 7, third receiver Harry Douglas will become the team’s No. 1. Douglas should be owned in all leagues, but he's never accumulated more than 498 receiving yards in a season.

Buy-low candidate: Robert Griffin III, QB, Washington Redskins

Coming off ACL surgery, Washington Redskins quarterback Robert Griffin III has looked rusty, rushing throws and hesitating to run the ball. He's averaging 18 rushing yards per game through four weeks, down from a 54-yard average a season ago. Still, RGIII has thrown for over 300 yards in three of the team's four games. More good news is on the horizon, as 10 of Washington's remaining 12 games are against opponents who allow 270 or more passing yards per game.

Sell-high candidate: Fred Jackson, RB, Buffalo Bills

Fred Jackson entered the season as the Bills' backup running back, but he leads the team in both rushing yards and touchdowns after collecting 53 yards and two scores last week. It might be a good time to unload Jackson, as Week 5 also saw starting running back C.J. Spiller display explosiveness that Jackson lacks. Spiller, who has been slowed with an ankle injury, ripped off a 54-yard touchdown run against the Browns. Look for the Bills' Week 6 opponent, the Cincinnati Bengals, to load the box and focus on stopping the run. They'll face practice squad call-up Thad Lewis after starting quarterback E.J. Manuel injured his knee.

Star to sit: Chris Johnson, RB, Tennessee Titans

Tennessee Titans running back Chris Johnson is 28, old by NFL standards. And he’s looked it this year, averaging 3.1 yards per carry. Furthermore, Johnson has just one rush for more than 20 yards and is yet to reach the painted grass this year. He isn’t even getting goal-line carries. The Titans play the Seahawks this week; just ask 49er fans about their run defense. Stay away from Johnson.

No-namer to start: Garrett Graham, TE, Houston Texans

On Wednesday, the Houston Texans placed starting tight end Owen Daniels on injured reserve/designated to return list. He ranked second on the team in receptions and targets, leaving a large void in the Texans’ passing game. In steps third-year pro Garrett Graham, who in limited time this year, has three receiving touchdowns. The Texans face the St. Louis Rams in Week 6 and Graham should see increased targets and production until Daniels' return.