STANFORD, Calif. -- Gennifer Brandon had 14 points and 12 rebounds and No. 7 California snapped fifth-ranked Stanford's 81-game winning streak against conference opponents with a commanding 67-55 win Sunday in the second meeting between the Bay Area rivals in six days.
Brittany Boyd added 19 points while Layshia Clarendon had 14 to help the Golden Bears beat a top-5 opponent for the first time since a 66-52 victory against No. 2 Rutgers on Nov. 22, 2008.
Mikayla Lyles scored 11 of her career-best-matching 14 points over the final 6:04 of the first half as Cal (13-2, 3-1 Pac-12) took control on the way to snapping Stanford's 10-game winning streak in the series and three-year run of dominance against the conference.
The Bears earned just their fourth victory in the last 46 meetings with Stanford (14-2, 3-1) - even more special now that both are among the nation's top-10.
They might just swap spots in the next poll now.
Chiney Ogwumike had 18 points and nine rebounds as Stanford dropped consecutive home games for the first time in 12 years.
Cal, whose only losses this season have come against Stanford and at No. 4 Duke, ended the Cardinal's impressive conference winning streak that dated to a 57-54 Bears win at Haas Pavilion in Berkeley on Jan. 18, 2009.
Stanford had stopped Cal's six-game winning streak with a 62-53 victory last Tuesday night.
Trailing 47-39 midway through the second half, Stanford squandered four chances to cut the lead to six. And Cal capitalized, getting a short jumper by Clarendon followed by a pair of free throws from Boyd at the 10:12 mark to make it 52-39. The Cardinal committed a shot-clock violation the next time down, their 14th turnover.
Stanford went 4:43 without scoring before Ogwumike's layin at 9:00. Clarendon immediately answered for Cal on the other end.
Stanford coach Tara VanDerveer sat struggling forward Mikaela Ruef to begin the second half after she only played 1 minute in the first and had three turnovers and a foul. Ruef checked in with 13:43 remaining in the game but quickly fouled out with two points and four rebounds.
The Pac-12 Conference championship will likely come down to these two, as everyone has expected for months.
Stanford, which has reached five straight Final Fours and is chasing a 13th straight regular-season conference crown - and 22nd overall - while opening Pac-12 play with five of eight games against teams ranked in The Associated Press poll.
Cal has never won or shared a conference title.
Stanford struggled against Cal's swarming, trapping man defense that forced 10 first-half turnovers.
The Bears also generated 14 offensive boards in the opening 20 minutes on the way to a 39-31 edge at the break despite shooting 33.3 percent to Stanford's 44 percent.
Ogwumike had 26 points on 11-for16 shooting, six rebounds, three blocks and three steals in Tuesday's win, but never got in her usual groove. She still shot 7 of 13.
Typically, the two matchups are spread out by about a month - but television dictated this season's schedule.
Stanford returned to Maples Pavilion for the first game on the home court since its 82-game home winning streak was snapped in a surprising 61-35 rout by Connecticut on Dec. 29.
The Cardinal lost back-to-back home games for the first time since Feb. 16 and March 3, 2001, against Cal and Southern California.
It doesn't get any easier, with No. 14 UCLA coming to campus Friday night.
Stanford's points were a record-low at home in a conference game. The previous was a 63-54 loss to No. Oregon on March 5, 1987. This also marked the Cardinal's first double-digit defeat at home in Pac-12 or Pac-10 play since losing 72-57 to Cal on Feb. 4, 2007.
Stanford made just 8 of 29 field goals in the second half and went 2 for 12 from long range for a 35.2-percent performance overall.
After shooting a season-low 30.2 percent Tuesday night, Cal began the game by missing its first 10 field-goal tries before Clarendon's steal and layin at the 13:48 mark of the first half.
The Bears were 3 for 19 - Clarendon 1 of 6 - early but Stanford was only slightly better at 4 for 10 and then missed 12 of its first 14 shots of the second half.
Boyd was whistled for her second foul with 6:23 remaining in the first half, but didn't have another and made 10 of 13 free throws. Lyles hit 4 of her 6 3-point tries.
Stanford's Rose Bowl champion football team showed off its hardware during a halftime ceremony.