OAKLAND -- Athletics rookie Aaron Brooks had a difficult time keeping his pitches down in the strike zone.
Each time he missed, the Astros took advantage.
Brooks gave up five runs and eight hits in four-plus innings during Oakland's 11-5 loss to Houston on Wednesday night.
"That's a good-hitting team, and not getting the ball down as many times as I wanted . it took its toll," Brooks said. "I have to keep trying to get better every day. Getting the ball down would be big."
The Astros hit four home runs to tie Toronto for the major league lead with 192. They also increased their advantage in the AL West to two games over Texas.
"We just have a lot of power," Houston manager A.J. Hinch said. "The long ball is a big part of our offense. If you make a mistake, we can hit it over the fence."
The A's have hit a home run in 15 consecutive games to tie the longest streak in the majors this season.
That was a moot point on a night when Brooks (1-3) struggled with his location.
"Early on his stuff was good," Melvin said. "He couldn't spot his fastball enough to keep it off the barrel of the bat."
McHugh (16-7) labored through his worst start in more than a month but got enough support to win his third straight. He allowed five runs and six hits in 5 1-3 innings, struck out five and walked two.
Houston's 76 wins are its most since 2010 when the club went 76-86.
"Our offense did an incredible job," McHugh said. "I've said it all year, you're never more than a swing out of it with our team. As a starting pitcher, if you can do the job of keeping it within a swing then you've done your job."
Rasmus, back in the lineup after sitting out two games with an illness, hit his 19th home run of the season into the second deck in right field on a full-count pitch from Brooks with two outs in the second.
After Conger's two-run single and an RBI double by Altuve helped extend the lead to 4-0, Gattis hit his 23rd homer as part of a three-run fifth.
Gomez homered off R.J. Alvarez in the sixth.
Gonzalez added his 10th home run in the seventh, giving the Astros 11 players with 10 or more. That ties the major league record set by the 2004 Detroit Tigers.
Chris Bassitt threw 35 pitches from 75 feet and Melvin said he is optimistic the right-hander will return this season. Bassitt hasn't pitched since Aug. 26 because of shoulder soreness.
Athletics RHP Jesse Chavez (7-14) pitches Friday in Texas. He has the most losses by an Oakland pitcher since 2010.