SAN FRANCISCO (14-5) at DALLAS (8-8)
Sunday, 4:25 p.m. ET, Fox
OPENING LINE - 49ers by 3 1/2
RECORD VS. SPREAD - 49ers 12-6-1, Cowboys 9-7-0
SERIES RECORD - Tied 16-16-1
LAST MEETING - Cowboys beat 49ers 27-24 in OT, Sept. 18, 2011
AP PRO32 RANKING - 49ers No. 6, Cowboys No. 25
STREAKS, STATS AND NOTES - 49ers coach Jim Harbaugh (3-0) only active coach with perfect record in multiple openers. He's only coach since 1970 merger to lead team to conference title game in each of first three seasons. ... Colin Kaepernick last year joined Hall of Famer Steve Young as only 49ers QBs with more than 3,000 yards passing and 500 yards rushing in season. ... 49ers RB Frank Gore needs 33 yards rushing to become 29th NFL player with 10,000 yards. ... 49ers' Vernon Davis leads NFL tight ends with 51 TDs since start of 2009, including playoffs. He has 15 TDs in past 18 games. ... 49ers' Antoine Bethea is leader among active safeties with 96 consecutive regular-season starts. ... Cowboys QB Tony Romo is 2-0 against 49ers with five TDs and no interceptions. Romo has all four 4,000-yard seasons and all three 30-touchdown seasons in history of franchise. ... Dez Bryant is only Dallas receiver with at least 90 catches, 1,000 yards and 10 touchdowns in consecutive seasons. ... Cowboys DE George Selvie had career-high seven sacks after signing during training camp. ... Cowboys CB Brandon Carr has at least 10 pass breakups in past five seasons, including 12 last year.