SAN FRANCISCO (1-1) at ARIZONA (2-0)
Sunday, 4:05 p.m., ET, FOX
OPENING LINE - 49ers by 2 1/2
SERIES RECORD - 49ers lead 28-17
LAST MEETING - 49ers beat Cardinals 23-20, Dec. 29, 2013
LAST WEEK - 49ers lost to Bears 28-20; Cardinals beat Giants 25-14
AP PRO32 RANKING - 49ers No. 8, Cardinals No. 6
STREAKS, STATS AND NOTES - 49ers have beaten Cardinals four straight and nine of past 10. ... Coach Jim Harbaugh is 5-1 against Arizona. ... San Francisco 18-7 on road under Harbaugh since he took over in 2011. Best winning percentage (.720) of NFL road team in that span. ... In 16 games vs. Arizona, TE Vernon Davis has 54 catches for 811 yards and 9 TDs. In 1st game against Cardinals last season, Davis caught 8 passes for 180 yards and 2 TDs. ... In 17 games vs Arizona, RB Frank Gore has 1,177 yards and rush TDs, 42 catches for 383 yards and 1 TD. ... In 2013 season finale against Cardinals, Gore got 51st rushing TD, passing Joe Perry and Roger Craig for franchise record. ... Arizona QB Carson Palmer missed game Sunday for 1st time since 2012 season finale. That 2012 game was only one he had missed since 2008. .. Bruce Arians' 12-6 start as Cardinals coach is franchise's best through 18 games since Norm Barry went 15-2-1 in 1925-26. Counting interim stint in Indianapolis, Arians 21-9 in regular season games. ... S Tyrann Mathieu was in on 5 plays vs Giants, his first game action since tearing ACL and MCL on his left knee in 13th game last year. ... Arizona DECalais Campbell had 10 tackles, a sack, 3 tackles for loss and a QB hit against Giants.