Ian Williams sustains broken left ankle vs. Seahawks
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SEATTLE – San Francisco 49ers nose tackle Ian Williams is out indefinitely with a broken left ankle, a source confirmed Sunday evening.

Williams, making his first career start for the 49ers, sustained the injury on his third defensive snap Sunday against the Seattle Seahawks. It was not immediately known how long Williams, a third-year professional, will be out of action. But the source told CSNBayArea.com that Williams will be out "a while." Pro Football Talk first reported Williams sustained a broken ankle.

Williams sustained the injury when Seahawks right guard J.R. Sweezy cut block him. Williams appeared to be in contact with center Max Unger at the time of Sweezy's low block. No penalty was called on the play.

Veteran Glenn Dorsey took over at nose tackle for the 49ers after Williams’ injury, and promptly sacked Russell Wilson. The 49ers signed Dorsey to a two-year, $6 million contract with a $2.285 signing bonus. Dorsey played his first five NFL seasons with the Kansas City Chiefs.

The 49ers have five healthy defensive linemen on their 53-man roster: Dorsey, Justin Smith, Ray McDonald, Demarcus Dobbs and Tony Jerod-Eddie. All but Jerod-Eddie were active for Sunday night’s game.

The 49ers expect rookie defensive linemen Tank Carradine and Quinton Dial to be available shortly after Week 6. Both Carradine (knee) and Dial (toe) are out for the first six weeks of the season while on the reserve/non-football injury list.

The 49ers released Will Tukuafu last week to make room on the 53-man roster for Dobbs who served a one-game suspension for violating the NFL's policy on substances of abuse. Rookie Mike Purcell is on the 49ers' practice squad.