SANTA CLARA -- Wide receiver Mario Manningham will miss his second postseason with the 49ers, as the club placed him on injured reserve Friday.
Manningham originally sustained tears to his ACL and posterior cruciate ligament on Dec. 23 of last season against the Seattle Seahawks. After spending the first eight weeks of the regular season on the physically-unable-to-perform list, Manningham played six games with little success.
Manningham caught eight passes for 85 yards in six games. Last week, he did not practice twice due to a knee injury. He did not practice on Thursday, either.
Just minutes before announcing the roster move, 49ers coach Jim Harbaugh said Manningham was consulting with doctors.
"We'll do what's in the best interest of his career," Harbaugh said. "He's got input in that. It's conversations between doctors and Mario at this point."
Manningham originally signed a two-year, $7.5 million contract with the 49ers in March 2012. After one season with the 49ers, Manningham accepted a pay cut from a scheduled base salary of $3.6 million to $1.8 million. He is scheduled to be an unrestricted free agent at the end of this season.
The 49ers will turn to rookie Quinton Patton as the 49ers’ No. 3 wide receiver behind Anquan Boldin and Michael Crabtree. Patton played 18 snaps Monday night in place of Manningham but did not have a pass thrown his way. In five games, Patton has one catch for zero yards.
Patton missed 10 games after sustaining a fractured right foot on Sept. 26 against the St. Louis Rams.